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____fire, all exits must be kept clear. 
A.In place ofB.Instead ofC.In case ofD.In spite of
C
in case of意為“以防萬一”,根據其賓語fire可判斷出“為了防止火災,一切出口都要清除干凈”。in place of 意為“代替”。instead of 意為“代替,而不是……”。in spite of 意為“不管”。
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